WebMD does not provide medical advice, diagnosis or treatment. Call your doctor right away if you have any of these serious side effects. When pregnancy is detected, Lisinopril and Hydrochlorothiazide Tablets should be discontinued as soon as possible. Your doctor may check your potassium level with blood tests. Thiazides may cause intermittent and slight elevation of serum calcium in the absence of known disorders of calcium metabolism.
Copyright Cerner Multum, Inc. In hemodynamic studies in patients with essential hypertension, blood pressure reduction was accompanied by a reduction in peripheral arterial resistance with little or no change in cardiac output and in heart rate. If it continues for a long time, the heart and arteries may not function properly.
Lisinopril/hydrochlorothiazide - oral, Prinzide, Zestoretic
This drug has a Black Box Warning. Do not share this medication with others. Other causes of volume depletion such as vomiting or diarrhea may also lead to a fall in blood pressure; patients should be advised to consult with their physician. The side effects see WARNINGS of lisinopril are generally rare and apparently independent of dose; those of hydrochlorothiazide are a mixture of dose-dependent phenomena primarily hypokalemia and dose-independent phenomena e.
Lisinopril does not appear to be bound to other serum proteins.
How to use Lisinopril-Hydrochlorothiazide Read the Patient Information Leaflet if available from your pharmacist before you start taking this medication and each time you get a refill. You are encouraged to report negative side effects of prescription drugs to the FDA. We appreciate your helpful feedback! Canada residents can call a provincial poison control center.
The following information includes only the average doses of lisinopril and hydrochlorothiazide. In addition to taking medication, making lifestyle changes will also help to control your blood pressure. Patients should be told not to use salt substitutes containing potassium without consulting their physician.
This drug can harm or be fatal to your unborn baby. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied.
Declining serum concentrations exhibit a prolonged terminal phase which does not contribute to drug accumulation. It is not a disclosure of all possible adverse or intended effects. ACE inhibitors have been associated with a higher rate of angioedema in black than in non-black patients.
Periodic determination of serum electrolytes to detect possible electrolyte imbalance should be performed at appropriate intervals. If this medication causes you to urinate more frequently, it is best to take it at least 4 hours before your bedtime to prevent having to get up to urinate.
Make sure you tell your doctor if you have any other medical problems, especially:. Thiazides may cause intermittent and slight elevation of serum calcium in the absence of known disorders of calcium metabolism.