Impaired spermatogenesis was observed in rats and dogs following day and 6-month oral exposures respectively.
In in vitro studies pilocarpine has been found to be an inhibitor of CYP2A6.
Pilocarpine Hydrochloride Tablets, USP
Never give it to other people even if their condition appears to be the same as yours. When taken with a high-fat meal, there was a decrease in the rate of absorption of pilocarpine from Salagen tablets.
Salagen may cause an increase in tears. Your doctor or pharmacist can often prevent or manage interactions by changing how you use your medications or by close monitoring. Nervous system disorders Very common: In a multiple-dose pharmacokinetic study in male volunteers following 2 days of 5 or 10 mg of oral pilocarpine hydrochloride tablets given at 8 a. Other, less serious side effects may also occur. Glaucoma is a common eye condition in which the fluid pressure inside the eye rises because of slowed fluid drainage from the eye.
Browse Drugs and Medicines. Be sure to mention any of the following: Continue to take pilocarpine and talk to your doctor if you experience. Instead, the best way to dispose of your medication is through a medicine take-back program. Points Scored for Increasing Abnormality. Stearic acid Film coating: Unless your doctor tells you otherwise, continue your normal diet.
Ocular formulations of pilocarpine have been reported to cause visual blurring which may result in decreased visual acuity, especially at night and in patients with central lens changes, and to cause impairment of depth perception.
Your doctor may start you on an average dose of pilocarpine and adjust your dose depending on how well your symptoms are controlled and the side effects you experience. Signs of overdose due to muscarinic effects may include abdominal cramps, diarrhoea, nausea and vomiting, involuntary defecation and urination, sweating, salivation, increased bronchial secretions, miosis, bradycardia and hypotension.
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All drugs may cause side effects. The recommended dose of pilocarpine hydrochloride tablets is 5 mg taken four times a day. Radiation therapy is a cancer-fighting technique.
Inan oral formulation of pilocarpine was approved by the FDA for the treatment of dry mouth caused by radiation therapy for head and neck cancera treatment that damages the salivary glands and reduces their production of saliva. These side effects may go away during treatment as your body adjusts to the medicine.
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