How to cite this comment: Respected addiction medicine providers liken disulfiram to both a cast on a fracture and a crutch to reduce weight-bearing on a fracture. This is not a complete list of side effects and others may occur. Antabuse may interact with isoniazid, monoamine oxidase inhibitors MAOIsbenzodiazepinestricyclic antidepressantswarfarin, metronidazole, theophylline, phenytoin, or lithium.
Disulfiram blocks this reaction at the intermediate stage by blocking acetaldehyde dehydrogenase. Discussions around the web. After you've been on Antabuse for a month you should have your liver tests repeated.
My main trouble now is dismantling my life, which is hard to do while badly depressed and acting on it makes the Most people just need to show some common sense when they're on Antabuse.
The Antabuse Reaction
I know I wouldn't have made it this far if not Generate a file for use with external citation management software. Antabuse works by making you sick to your stomach if you have a drink. A very unpleasant reaction occurs when a patient under disulfiram treatment ingests alcohol. The ideal candidate for disulfiram might well be physiologically young and vigorous; be on no other medications; have no evidence of cardiovascular, cardiopulmonary, hepatobiliary, renal or neurologic disorders or comorbid psychosis; have fully accepted the neuropsychiatric diagnosis of alcohol dependency with ongoing step sponsorship and step work; have a caring significant other working a step program of recovery to witness and affirm the disulfiram oral pharmacotherapy; and not be looking for a quick fix.
Discussions around the web
Related Health Alcoholism Liver Disease. Acetaldehyde dehydrogenase inhibitors Alcohol abuse Antiprotozoal agents Danish inventions Dopamine beta hydroxylase inhibitors Thiuram disulfides Disulfiram-like drugs.
Nevertheless, the increased awareness of the impact of alcohol dependency on the lives of our patients, which may include some of our alcohol-dependent colleagues; the varying health care expectations of ethnic groups; the documentation of the effects of alcohol on the incidence of disorders, including cancer; the increased awareness of self-help groups; and the growing awareness of the role of spirituality in the lives of our alcohol-dependent patients may support a reasonable judgment in favor of a focused health care provision of disulfiram in selected recovering alcohol-dependent patients.
Chlorine -containing products Lindane. Add to My Bibliography. In severe reactions there may be respiratory depression, cardiovascular collapse, arrhythmias, myocardial infarction, acute congestive heart failure, unconsciousness, convulsions, and death.
When disulfiram creates complexes with metals dithiocarbamate complexesit is a proteasome inhibitor  and can represent a new approach to proteasome inhibition. Check symptoms - is depression caused by a drug or a condition? Journal of Clinical Investigation. We need a better treatment right now. Antabuse liberates you, if you use a little common sense. But once in my early 20s I became massively depressed and Journal of the American Medical Association.